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Fakultät Bio- und Chemieingenieurwesen

M. Sc. Jana Kerkhoff

Controlling Quality and Kinetics of Drying Processes for ASDs

11/16/2020 - 07/31/2024

Amorphous solid dispersions (ASDs) are popular pharmaceutical formulation to improve the bioavailability of poorly water-soluble drug candidates. ASDs are produced via solvent-based processes with subsequent drying. This project focuses on the equilibrium and drying kinetics of pharmaceutical-relevant polymers and ASDs by coupling thermodynamic and diffusion modeling.