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Fakultät Bio- und Chemieingenieurwesen

Co-Solute and Co-Solvent Influence on the Reaction Equilibria of Enzymatic Catalyzed Reactions

01/01/2016 - 07/10/2019

In literature co-solvent and co-solute effects on thermodynamic reaction equilibria of only a few enzymatic reactions were studied so far. In most cases the reaction media is pure water or a low concentrated buffered solution. This simplification of the highly non-ideal solutions present in cells leads to a lack of information and understanding of these complex systems. As a first approach to understand these complex interactions, this work is focused on the prediction of co-solvents and co-solute effects on the reaction equilibria of enzyme-catalyzed reactions.