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SCIENTIFIC HIGHLIGHTS 2019

Thermodynamics of Glycolysis

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  • Research Highlights
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New standard Gibbs energy of reaction values for glycolysis reactions determined from equilibrium measurements combined with activity coefficients

For many organisms, glycolysis is a central metabolic pathway that provides energy and synthesis of precursors for further
biosyntheses. The reaction equilibria of the single glycolytic reaction steps was investigated in this work to gain new
thermodynamically-consistent standard data. The availability of such new data allows applying systems-biology tools for
future investigations of the feasibility of the pathway, or parts of it, in a cell or even in a bioreactor.